Josiah Samuel Smith's biological transformation vs. his will to maintain control and authority

The Doctor seizes upon the sudden activation of the mansion’s stained glass wards, which begin pulsing ominously at the top of the stairs. With the alarm shrieking through the halls, …

The Doctor’s decisive counter to Josiah’s experiment—redirecting a steam vent’s scalding rush into his face—grants Ace the opening to seize his revolver. But the mansion’s forces now turn against Josiah: …

Ace and the Doctor emerge from the lift into the entrance hall to find Josiah rapidly succumbing to his own horrific transformation. Josiah orders his staff to secure the house …